Which option describes the action of beta-blockers on pulse rate?

Beta-blockers are medications that primarily work by blocking the effects of adrenaline on beta-adrenergic receptors in the body. This action leads to a reduction in heart rate, resulting in a decrease in pulse rate. When beta-blockers are administered, they inhibit the physiological response that increases heart rate during times of stress or physical exertion. This makes them effective in treating various cardiovascular conditions such as hypertension, arrhythmias, and other heart diseases.

The decrease in pulse rate is significant for patients with conditions that could benefit from a lowered heart rate, as it allows the heart to work more efficiently and reduces the risk of adverse events related to elevated heart rates. Given the mechanism of action, it is clear why the correct choice describes the effect of beta-blockers on pulse rate accurately.