What temperature at the periphery of an osteotomy leads to bone resorption?

The temperature at the periphery of an osteotomy that leads to bone resorption is 47 degrees Celsius. This specific temperature is critical because it represents a threshold above which bone tissue begins to experience thermal injury, leading to detrimental effects on bone healing.

At elevated temperatures, particularly around 47 degrees, bone cells can be negatively affected in such a way that they experience apoptosis (cell death) or necrosis, undermining the biological processes necessary for healing and regeneration. The thermal sensitivity of bone is particularly high within this range, as bone cells, including osteoblasts and osteoclasts, are essential for maintaining bone health and integrity.

In contrast, temperatures lower than this threshold typically do not invoke significant adverse biological responses, allowing for normal cellular activities involved in bone repair and regeneration to proceed unhindered. This knowledge is vital for practitioners when considering surgical techniques and thermal effects during procedures that might involve osteotomies to ensure optimal healing and avoid complications associated with heat-induced bone resorption.