What effect do beta-blockers have on pulse rate?

Beta-blockers are a class of medications that primarily work by blocking the effects of the hormone epinephrine (also known as adrenaline) on beta adrenergic receptors. When these receptors are inhibited, beta-blockers lead to a decrease in heart rate as part of their overall cardiovascular effects. This reduction in heart rate occurs because beta-blockers diminish the sympathetic nervous system's influence on the heart, which typically increases heart rate and force of contraction during stress or fight-or-flight situations.

By decreasing the heart rate, beta-blockers are often used in the management of various cardiovascular conditions, including hypertension, arrhythmias, and even heart failure. Consequently, the effect of beta-blockers on pulse rate is a significant aspect of their therapeutic action, making the correct answer that beta-blockers decrease pulse rate.